"The discovery and understanding of chaos produced a rethinking of many core tenets of science:
1) Seemingly random behavior can emerge from deterministic systems, with no external source of randomness.
2) The behavior of some simple, deterministic systems can be impossible, even in principle, to predict in the long term, due to sensitive dependence on initial conditions."
I think Melanie Mitchell made an useful guide for cancer researchers. Hopefully, they will read her book.